Brief
description of system
EcoR124I
is a Type I restriction modification system. It is a protein complex made up
of a core Methyltransferase (MTase) consisting of 1 HsdS (Specificity)
subunit and 2 HsdM (Methylase) subunits. A first then a second HsdR subunit
bind to the MTase to form a restriction deficient R1-complex
and then a restriction-proficient Endonuclease (ENase) complex